2009年6月3日水曜日

トマトピル‘心臓病’を負かす

トマトピル‘心臓病’を負かす

トマト。
トマトはリコピンの豊富な供給源である。

科学者達は、トマトから作られた天然サプリメントを毎日摂取すると、心臓病や脳卒中を避けることが出来る、と言っている。

トマトピルは地中海ダイエットの活性成分であるリコピンを含んでいて、このリコピンは動脈を詰まらせる可能性のある“悪玉”LDLコレステロールを阻害する。

Aterononは、ケンブリッジ大学のバイオテクノロジー新会社によって作られたのだが、栄養補助食品として市場に出され、店で販売されるだろう。

専門家達は、その治療の効果を知るためにはもっと多くの試験が必要であると言った。

心臓病を持っている約150人が関係した予備試験では、Aterononは8週間以内に血中の有害な脂肪の酸化をほぼゼロまで減らすことが出来ることを示している、と月曜日Aterononを売り出す時に英国循環器病学会の会合で報告されるであろう。

心臓病患者や高いリスクをもった人達への我々の忠告は、かかりつけの医者によって処方される証明済みの医薬に頼り、沢山の新鮮な果物や野菜を食べることによって地中海ダイエットの恩恵を得ることを目指すことである。
英国心臓財団のPeter Weissberg教授

Cambridge Theranostics株式会社のために、ケンブリッジのAddenbrook病院で更なる研究プロジェクトを率いる神経科学者Peter Kirkpatrickは、サプリメントは現在高コレステロール治療のために医者が使っているスタチン薬よりずっと効果的であろう、と言った。

しかし英国心臓財団のPeter Weissberg教授は言った:“いつものように、我々は人々に次のことを警告します、新しい薬或は変更された“天然”製品を摂取する前にそれが利益を提供することを臨床的に証明されるのを待つようにと。
“Aterononにそのような証拠を与えるためには暫くの時間といくつかの臨床試験が必要であろう。

“その間は、心臓病患者や高いリスクをもった人達への我々の忠告は、かかりつけの医者によって処方される証明済みの医薬に頼り、沢山の新鮮な果物や野菜を食べることによって地中海ダイエットの恩恵を得ることを目指すことである”

彼は、英国心臓財団はその製品の開発を支持しているケンブリッジ大学の基礎科学をいくらかサポートした、と言った。 

コレステロール・チャリティー・ハート英国の評議員であるAnthony Leeds教授は言った:“新しいリコピン製品Aterononは高血中コレステロールの治療への全く新しいアプローチであり、エキサイチングな可能性を開きます。”

彼は、予備調査結果は“非常に有望”である、と言った。

リコピンはトマトの皮に含まれている抗酸化物質で、トマトに赤い色を与えている。しかし自然の形で摂取されるリコピンは吸収が悪い。

Aterononは、もとはNestleによって開発された精製した、より吸収がよい形のリコピンを含んでいる。

脳卒中協会のPeter Coleman博士は言った:“我々は、抗酸化物質に富んだ食事はプラークの形成を減らすために有益であること知っているので、この研究の調査結果を歓迎します。”

2009年6月1日月曜日

Tomato pill 'beats heart disease'





Tomatoes
Tomatoes are a rich source of lycopene

Scientists say a natural supplement made from tomatoes, taken daily, can stave off heart disease and strokes.

The tomato pill contains an active ingredient from the Mediterranean diet - lycopene - that blocks "bad" LDL cholesterol that can clog the arteries.

Ateronon, made by a biotechnology spin-out company of Cambridge University, is being launched as a dietary supplement and will be sold on the high street.

Experts said more trials were needed to see how effective the treatment is.

Preliminary trials involving around 150 people with heart disease indicate that Ateronon can reduce the oxidation of harmful fats in the blood to almost zero within eight weeks, a meeting of the British Cardiovascular Society will be told at Ateronon's launch on Monday.

Our advice to heart disease patients or those at high risk is to rely on proven medications prescribed by their doctor, and aim to get the benefits of a Mediterranean diet by eating plenty of fresh fruit and veg
Professor Peter Weissberg of the British Heart Foundation

Neuroscientist Peter Kirkpatrick, who will lead a further research project at Addenbrooke's Hospital in Cambridge on behalf of Cambridge Theranostics Ltd, said the supplement could be much more effective than statin drugs that are currently used by doctors to treat high cholesterol.

But Professor Peter Weissberg of the British Heart Foundation said: "As always, we caution people to wait for any new drug or modified 'natural' product to be clinically proven to offer benefits before taking it.

"It will take some time, and several clinical trials, to provide such evidence for Ateronon.

"In the meantime, our advice to heart disease patients or those at high risk is to rely on proven medications prescribed by their doctor, and aim to get the benefits of a Mediterranean diet by eating plenty of fresh fruit and veg."

He said the British Heart Foundation had supported some of the basic science at Cambridge University underpinning the development of the product.

Professor Anthony Leeds, trustee of the cholesterol charity Heart UK, said: "The new lycopene product Ateronon represents an entirely new approach to the treatment of high blood cholesterol and opens up the exciting possibility."

He said the preliminary findings were "very promising".

Lycopene is an antioxidant contained in the skin of tomatoes which gives them their red colour. But lycopene ingested in its natural form is poorly absorbed.

Ateronon contains a refined, more readily absorbed version of lycopene that was originally developed by Nestle.

Dr Peter Coleman of The Stroke Association said: "We know that diets rich in antioxidants are beneficial in reducing the plaque build up and welcome the findings of this research."

イギリスのMETRO新聞から!

Lyc-o-matoへようこそ!

Tomato Pill Aims To Tackle Heart Disease

10:54am UK, Monday June 01, 2009

Heart experts claim they have devised a pill with all the health benefits of tomatoes which could save hundreds of lives.

Tomatoes

A pill containing a key ingredient of tomatoes is developed by scientists

Scientists say they have found a way to put all the goodness of the antioxidants in the skin of ripe tomatoes into a tablet that can slash cholesterol levels.

The new pill, called Ateronon, has been developed by Cambridge University subsidiary Cambridge Theranostics Ltd and could be on sale in high street pharmacists from July onwards for as little as £1 a day.

It was being launched at the conference of the British Cardiovascular Society in London and chief executive Gunter Schmidt said: "This has the potential to affect everybody. We are very excited about it."

Ripe tomato skins contain a substance called lycopene, which is thought to protect against cancer, heart disease and strokes.

Mediterranean-style diets are rich in tomatoes and people from the region have much lower rates of heart disease than other parts of the world.

Tablet

Pill could be on sale soon

But lycopene cannot be absorbed by the body unless it has been broken down before being eaten, such as when tomatoes are cooked and processed.

Ateronon is developed from a lycopene and contains other compounds found in natural foods.

The manufacturers claim that in tests on 150 people suffering from heart disease, it appeared effective on all of them.

Heart attacks and cardiovascular disease kill 200,000 people in Britain before the age of 75.

Neuroscientist Peter Kirkpatrick will lead a further research project at Cambridge's Addenbrookes Hospital.

He said the new treatment could be "much more effective" than the current treatment of statins, which are ineffective in almost two-thirds of people.

But critics say the drug has still to undergo full clinical trials.

Sky News health correspondent Thomas Moore said: "The manufacturers of Ateronon may well have condensed all the goodness in a tomato into an easy-to-take pill.

"But until they have done proper clinical trials there is no proof that it will make you live longer and healthier.

"The pill costs more than £1 a day - and you can buy a lot of tomatoes for that. They probably taste better too."

Tomato pill that cleans arteries

Ateronon could help save thousands of lives, say scientists
Ateronon could help save thousands of lives, say scientists

A new health pill based on tomatoes could 'save lives on a global basis' by drastically unclogging the fat from arteries, scientists say.

Ateronon, launched today in Britain, is said to offer the benefits of a Mediterranean diet, which is known to prevent heart disease and strokes.

The supplement, which uses lycopene, a chemical found in the skin of ripe tomatoes, has been shown to wipe out nearly all harmful fats in the blood within eight weeks. Now, it is being clinically tested to see if it can even reverse heart disease as well as preventing it.

TV doctor Rob Hicks predicted it could 'potentially extend life and also possibly save lives on a global basis'.

Lycopene has long been known as a powerful anti-oxidant which controls cholesterol by stopping fats breaking up in the blood. Ateronon, which will cost £35 a month when it goes on sale this month, is being hailed as a breakthrough because, unlike the natural form, it is easy to absorb.

Each pill is the equivalent of eating three kilos of ripe tomatoes a day.

It has been developed by Cambridge University spin-off Cambridge Theranostics Ltd and will be launched today at a medical conference in London.

CTL's chief executive Gunter Schmidt said: 'We are anxious that its capabilities are taken seriously by doctors and it is not dismissed as just another food supplement.'

A year-long trial to see if it can rev­erse the effects of heart disease in 200 patients will begin shortly at Harvard.

A British study will also look at its use for brain haemorrhage patient.

But the British Tomato Growers Association, warned: 'There's far more evidence for the benefits of nutrient-rich natural food than there is for any dietary supplement.'